Cellular and humoral immunity elicited by an Influenza A polyvalent virosomal vaccine in pigs.
Cellular and humoral immunity elicited by an Influenza A polyvalent virosomal vaccine in pigs.
Author(s): HAACH, V.; BASTOS, A. P. A.; GAVA, D.; FONSECA, F. M. da; MORES, M. A. Z.; COLDEBELLA, A.; FRANCO, A. C.; SCHAEFER, R.
Summary: Influenza A virus (IAV) causes economic losses to the swine industry and public health concerns. The IAV is endemic in pigs and genetically and antigenically distinct virus lineages of subtypes H1N1, H1N2 and H3N2 circulate in different geographic regions with limited cross-protection (1, 2). The co-circulation of distinct IAV lineages associated with rapid viral evolution challenges the development of effective vaccines. The aim of this study was to evaluate the immunogenicity of an adjuvanted virosome-based influenza vaccine containing the hemagglutinin (HA) of H1N1pdm, H1N2 and H3N2.
Publication year: 2022
Types of publication: Paper in annals and proceedings
Unit: Embrapa Swine & Poultry
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